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Public release date: 29-Mar-2012[ | E-mail |
Share ] Contact: Alissa J. Cruz
media@gastro.org
301-272-1603
American Gastroenterological Association
Patients with irritable bowel syndrome (IBS) have a significantly greater prevalence of early adverse life events , including general trauma as well as physical, emotional and sexual abuse, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association.
"Various types of early adverse events are associated with the development of irritable bowel syndrome, particularly among women," said Lin Chang, MD, of the David Geffen School of Medicine at the University of California Los Angeles and lead author of this study. "Addressing early adverse events and associated psychological symptoms in these patients is important and may help guide management approaches that reduce symptoms and improve overall well-being."
Although associations between an abuse history and IBS have been reported before, in the current study, researchers aimed to assess simultaneously the association of a range of traumatic events not limited to abuse with IBS and the impact of differences in gender and psychological factors on these associations. Men and women with IBS who were 18 years of age and older were recruited primarily from community advertisements in the greater Los Angeles area. Early adverse life events were evaluated in 294 IBS patients (79 percent were women) and 435 controls (77 percent were women). Validated questionnaires assessed gastrointestinal, psychological and somatic symptoms.
Compared with controls, IBS patients reported a higher prevalence of general trauma, physical punishment, emotional abuse and sexual events. These events included witnessing violence, mental illness in the family, emotional abuse, and being forced to touch intimate parts of a person's body or have genital sex. These significant differences were observed mainly in women. Emotional abuse was the strongest predictor of IBS. Further, the strength of the relationship between the early trauma and IBS was reduced after controlling for the presence of psychological and other non-gastrointestinal symptoms.
Early adverse life events refer to traumatic experiences during childhood encompassing physical, sexual or emotional abuse, as well as discordant relationships with a primary caretaker, or the loss of a parent. These events appear to be associated with an increased vulnerability toward developing functional gastrointestinal disorders, including IBS.
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To learn more about IBS, please read the AGA brochure, "IBS: A Patient's Guide to Living with Irritable Bowel Syndrome" at http://www.gastro.org/patient-center/digestive-conditions/irritable-bowel-syndrome.
About the AGA Institute
The American Gastroenterological Association is the trusted voice of the GI community. Founded in 1897, the AGA has grown to include 17,000 members from around the globe who are involved in all aspects of the science, practice and advancement of gastroenterology. The AGA Institute administers the practice, research and educational programs of the organization. http://www.gastro.org.
About Clinical Gastroenterology and Hepatology
The mission of Clinical Gastroenterology and Hepatology is to provide readers with a broad spectrum of themes in clinical gastroenterology and hepatology. This monthly peer-reviewed journal includes original articles as well as scholarly reviews, with the goal that all articles published will be immediately relevant to the practice of gastroenterology and hepatology. For more information, visit http://www.cghjournal.org.
Like AGA on Facebook.
Join AGA on LinkedIn.
Follow us on Twitter @AmerGastroAssn.
Check out our videos on YouTube.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 29-Mar-2012[ | E-mail |
Share ] Contact: Alissa J. Cruz
media@gastro.org
301-272-1603
American Gastroenterological Association
Patients with irritable bowel syndrome (IBS) have a significantly greater prevalence of early adverse life events , including general trauma as well as physical, emotional and sexual abuse, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association.
"Various types of early adverse events are associated with the development of irritable bowel syndrome, particularly among women," said Lin Chang, MD, of the David Geffen School of Medicine at the University of California Los Angeles and lead author of this study. "Addressing early adverse events and associated psychological symptoms in these patients is important and may help guide management approaches that reduce symptoms and improve overall well-being."
Although associations between an abuse history and IBS have been reported before, in the current study, researchers aimed to assess simultaneously the association of a range of traumatic events not limited to abuse with IBS and the impact of differences in gender and psychological factors on these associations. Men and women with IBS who were 18 years of age and older were recruited primarily from community advertisements in the greater Los Angeles area. Early adverse life events were evaluated in 294 IBS patients (79 percent were women) and 435 controls (77 percent were women). Validated questionnaires assessed gastrointestinal, psychological and somatic symptoms.
Compared with controls, IBS patients reported a higher prevalence of general trauma, physical punishment, emotional abuse and sexual events. These events included witnessing violence, mental illness in the family, emotional abuse, and being forced to touch intimate parts of a person's body or have genital sex. These significant differences were observed mainly in women. Emotional abuse was the strongest predictor of IBS. Further, the strength of the relationship between the early trauma and IBS was reduced after controlling for the presence of psychological and other non-gastrointestinal symptoms.
Early adverse life events refer to traumatic experiences during childhood encompassing physical, sexual or emotional abuse, as well as discordant relationships with a primary caretaker, or the loss of a parent. These events appear to be associated with an increased vulnerability toward developing functional gastrointestinal disorders, including IBS.
###
To learn more about IBS, please read the AGA brochure, "IBS: A Patient's Guide to Living with Irritable Bowel Syndrome" at http://www.gastro.org/patient-center/digestive-conditions/irritable-bowel-syndrome.
About the AGA Institute
The American Gastroenterological Association is the trusted voice of the GI community. Founded in 1897, the AGA has grown to include 17,000 members from around the globe who are involved in all aspects of the science, practice and advancement of gastroenterology. The AGA Institute administers the practice, research and educational programs of the organization. http://www.gastro.org.
About Clinical Gastroenterology and Hepatology
The mission of Clinical Gastroenterology and Hepatology is to provide readers with a broad spectrum of themes in clinical gastroenterology and hepatology. This monthly peer-reviewed journal includes original articles as well as scholarly reviews, with the goal that all articles published will be immediately relevant to the practice of gastroenterology and hepatology. For more information, visit http://www.cghjournal.org.
Like AGA on Facebook.
Join AGA on LinkedIn.
Follow us on Twitter @AmerGastroAssn.
Check out our videos on YouTube.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-03/aga-cte032912.php
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